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Overproduction of l-Lysine from Methanol by Methylobacillus glycogenes Derivatives Carrying a Plasmid with a Mutated dapA Gene

The dapA gene, encoding dihydrodipicolinate synthase (DDPS) partially desensitized to inhibition by l-lysine, was cloned from an l-threonine- and l-lysine-coproducing mutant of the obligate methylotroph Methylobacillus glycogenes DHL122 by complementation of the nutritional requirement of an Escheri...

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Publicado en:Appl Environ Microbiol
Autores principales: Motoyama, Hiroaki, Yano, Hiroshi, Terasaki, Yoko, Anazawa, Hideharu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11425723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.67.7.3064-3070.2001
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