Overproduction of l-Lysine from Methanol by Methylobacillus glycogenes Derivatives Carrying a Plasmid with a Mutated dapA Gene

The dapA gene, encoding dihydrodipicolinate synthase (DDPS) partially desensitized to inhibition by l-lysine, was cloned from an l-threonine- and l-lysine-coproducing mutant of the obligate methylotroph Methylobacillus glycogenes DHL122 by complementation of the nutritional requirement of an Escheri...

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Bibliographische Detailangaben
Hauptverfasser: Motoyama, Hiroaki, Yano, Hiroshi, Terasaki, Yoko, Anazawa, Hideharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Physiology and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC92982/
https://ncbi.nlm.nih.gov/pubmed/11425723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.7.3064-3070.2001
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