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Transformation of Amoxapine by Cunninghamella elegans

We examined Cunninghamella elegans to determine its ability to transform amoxapine, a tricyclic antidepressant belonging to the dibenzoxazepine class of drugs. Approximately 57% of the exogenous amoxapine was metabolized to three metabolites that were isolated by high-performance liquid chromatograp...

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Bibliografiske detaljer
Main Authors: Moody, Joanna D., Zhang, Donglu, Heinze, Thomas M., Cerniglia, Carl E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC92200/
https://ncbi.nlm.nih.gov/pubmed/10919836
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