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Identification and Characterization of a Bile Acid 7α-Dehydroxylation Operon in Clostridium sp. Strain TO-931, a Highly Active 7α-Dehydroxylating Strain Isolated from Human Feces

Clostridium sp. strain TO-931 can rapidly convert the primary bile acid cholic acid to a potentially toxic compound, deoxycholic acid. Mixed oligonucleotide probes were used to isolate a gene fragment encoding a putative bile acid transporter from Clostridium sp. strain TO-931. This DNA fragment had...

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Bibliografiset tiedot
Päätekijät: Wells, James E., Hylemon, Phillip B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC91949/
https://ncbi.nlm.nih.gov/pubmed/10698778
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