d-Pantothenate Synthesis in Corynebacterium glutamicum and Use of panBC and Genes Encoding l-Valine Synthesis for d-Pantothenate Overproduction

d-Pantothenate is synthesized via four enzymes from ketoisovalerate, which is an intermediate of branched-chain amino acid synthesis. We quantified three of these enzyme activities in Corynebacterium glutamicum and determined specific activities ranging from 0.00014 to 0.001 μmol/min mg (protein)(−1...

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Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Sahm, Hermann, Eggeling, Lothar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Physiology and Biotechnology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC91285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.65.5.1973-1979.1999
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