TEM-89 β-Lactamase Produced by a Proteus mirabilis Clinical Isolate: New Complex Mutant (CMT 3) with Mutations in both TEM-59 (IRT-17) and TEM-3

TEM-89 (CMT-3) is the first complex mutant β-lactamase produced by a clinical strain of Proteus mirabilis (strain Pm 631). This new enzyme, which has a pI of 6.28, is derived from TEM-3 and has a single amino acid substitution also encountered in TEM-59 (inhibitor-resistant TEM β-lactamase IRT-17):...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Neuwirth, Catherine, Madec, Stephanie, Siebor, Eliane, Pechinot, Andre, Duez, Jean-Marie, Pruneaux, Michele, Fouchereau-Peron, Martine, Kazmierczak, Antoine, Labia, Roger
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11709345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.12.3591-3594.2001
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