TEM-89 β-Lactamase Produced by a Proteus mirabilis Clinical Isolate: New Complex Mutant (CMT 3) with Mutations in both TEM-59 (IRT-17) and TEM-3

TEM-89 (CMT-3) is the first complex mutant β-lactamase produced by a clinical strain of Proteus mirabilis (strain Pm 631). This new enzyme, which has a pI of 6.28, is derived from TEM-3 and has a single amino acid substitution also encountered in TEM-59 (inhibitor-resistant TEM β-lactamase IRT-17):...

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Main Authors: Neuwirth, Catherine, Madec, Stephanie, Siebor, Eliane, Pechinot, Andre, Duez, Jean-Marie, Pruneaux, Michele, Fouchereau-Peron, Martine, Kazmierczak, Antoine, Labia, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90874/
https://ncbi.nlm.nih.gov/pubmed/11709345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3591-3594.2001
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