Antifungal Activities of Two New Azasordarins, GW471552 and GW471558, in Experimental Models of Oral and Vulvovaginal Candidiasis in Immunosuppressed Rats

Sordarins constitute a new class of antifungal agents with a novel mechanism of action involving the selective inhibition of fungal protein synthesis. A further evolution of this class of antifungals has led to a new family of sordarin derivatives called azasordarins. The therapeutic efficacies of t...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Martinez, Antonio, Ferrer, Santiago, Santos, Inmaculada, Jimenez, Elena, Sparrowe, John, Regadera, Javier, De Las Heras, Federico Gomez, Gargallo-Viola, Domingo
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Experimental Therapeutics
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11709301/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.12.3304-3309.2001
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