Antifungal Activities of Two New Azasordarins, GW471552 and GW471558, in Experimental Models of Oral and Vulvovaginal Candidiasis in Immunosuppressed Rats

Sordarins constitute a new class of antifungal agents with a novel mechanism of action involving the selective inhibition of fungal protein synthesis. A further evolution of this class of antifungals has led to a new family of sordarin derivatives called azasordarins. The therapeutic efficacies of t...

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Autors principals: Martinez, Antonio, Ferrer, Santiago, Santos, Inmaculada, Jimenez, Elena, Sparrowe, John, Regadera, Javier, De Las Heras, Federico Gomez, Gargallo-Viola, Domingo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90830/
https://ncbi.nlm.nih.gov/pubmed/11709301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3304-3309.2001
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