Staphylococcus aureus Mutants Selected by BMS-284756

BMS-284756, a novel des-fluoro(6)-quinolone, was used to select for in vitro mutants of Staphylococcus aureus ISP794. Step mutants were obtained, and the quinolone resistance-determining regions of four target genes, gyrA, gyrB, grlA, and grlB, were sequenced. The data suggest that DNA gyrase is the...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Discotto, L. F., Lawrence, L. E., Denbleyker, K. L., Barrett, J. F.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2001
Teme:	Mechanisms of Resistance
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600399/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3273-3275.2001
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