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Genetic Analysis of Multiple Loci Suggests that Mutations in the Pneumocystis carinii f. sp. hominis Dihydropteroate Synthase Gene Arose Independently in Multiple Strains

To determine if mutations in the dihydropteroate synthase (DHPS) gene of Pneumocystis carinii f. sp. hominis arose in a single strain that was subsequently widely disseminated, we examined four genomic regions of 22 P. carinii clinical isolates selected based on the absence or presence of mutations...

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Detalhes bibliográficos
Main Authors: Ma, Liang, Kovacs, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90808/
https://ncbi.nlm.nih.gov/pubmed/11600382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3213-3215.2001
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