Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia. The results suggest that DHPS mutations can be selected...

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Bibliographic Details
Main Authors: Nahimana, Aimable, Rabodonirina, Meja, Helweg-Larsen, Jannik, Meneau, Isabelle, Francioli, Patrick, Bille, Jacques, Hauser, Philippe M.
Format: Artigo
Language:Inglês
Published: Centers for Disease Control and Prevention 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023424/
https://ncbi.nlm.nih.gov/pubmed/12890330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid0907.020753
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