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Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia. The results suggest that DHPS mutations can be selected...

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Bibliographische Detailangaben
Hauptverfasser: Nahimana, Aimable, Rabodonirina, Meja, Helweg-Larsen, Jannik, Meneau, Isabelle, Francioli, Patrick, Bille, Jacques, Hauser, Philippe M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Centers for Disease Control and Prevention 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023424/
https://ncbi.nlm.nih.gov/pubmed/12890330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid0907.020753
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