Pharmacodynamics and Bactericidal Activity of Moxifloxacin in Experimental Escherichia coli Meningitis

Moxifloxacin, an 8-methoxyquinolone with broad-spectrum activity in vitro, was studied in the rabbit model of Escherichia coli meningitis. The purposes of this study were to evaluate the bactericidal effectiveness and the pharmacodynamic profile of moxifloxacin in cerebrospinal fluid (CSF) and to co...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Rodriguez-Cerrato, Violeta, McCoig, Cynthia C., Michelow, Ian C., Ghaffar, Faryal, Jafri, Hasan S., Hardy, Robert D., Patel, Chetan, Olsen, Kurt, McCracken, George H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3092-3097.2001
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