Pharmacodynamics and Bactericidal Activity of Moxifloxacin in Experimental Escherichia coli Meningitis

Moxifloxacin, an 8-methoxyquinolone with broad-spectrum activity in vitro, was studied in the rabbit model of Escherichia coli meningitis. The purposes of this study were to evaluate the bactericidal effectiveness and the pharmacodynamic profile of moxifloxacin in cerebrospinal fluid (CSF) and to co...

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Main Authors: Rodriguez-Cerrato, Violeta, McCoig, Cynthia C., Michelow, Ian C., Ghaffar, Faryal, Jafri, Hasan S., Hardy, Robert D., Patel, Chetan, Olsen, Kurt, McCracken, George H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90787/
https://ncbi.nlm.nih.gov/pubmed/11600361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3092-3097.2001
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