Mechanisms of Streptomycin Resistance: Selection of Mutations in the 16S rRNA Gene Conferring Resistance

Chromosomally acquired streptomycin resistance is frequently due to mutations in the gene encoding the ribosomal protein S12, rpsL. The presence of several rRNA operons (rrn) and a single rpsL gene in most bacterial genomes prohibits the isolation of streptomycin-resistant mutants in which resistanc...

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Main Authors: Springer, Burkhard, Kidan, Yishak G., Prammananan, Therdsak, Ellrott, Kerstin, Böttger, Erik C., Sander, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90746/
https://ncbi.nlm.nih.gov/pubmed/11557484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2877-2884.2001
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