Mechanisms of Streptomycin Resistance: Selection of Mutations in the 16S rRNA Gene Conferring Resistance

Chromosomally acquired streptomycin resistance is frequently due to mutations in the gene encoding the ribosomal protein S12, rpsL. The presence of several rRNA operons (rrn) and a single rpsL gene in most bacterial genomes prohibits the isolation of streptomycin-resistant mutants in which resistanc...

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Autors principals: Springer, Burkhard, Kidan, Yishak G., Prammananan, Therdsak, Ellrott, Kerstin, Böttger, Erik C., Sander, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90746/
https://ncbi.nlm.nih.gov/pubmed/11557484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2877-2884.2001
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