Inhibition of Trypsin-Like Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis by Tetracycline and Its Analogues

Extracellular cysteine proteinases, referred to as gingipains, are considered important virulence factors for Porphyromonas gingivalis, a bacterium recognized as a major etiologic agent of chronic periodontitis. We investigated the effect of tetracycline and its analogues, doxycycline and minocyclin...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Imamura, Takahisa, Matsushita, Kenji, Travis, James, Potempa, Jan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Mechanisms of Action: Physiological Effects
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2871-2876.2001
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