Inhibition of Trypsin-Like Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis by Tetracycline and Its Analogues

Extracellular cysteine proteinases, referred to as gingipains, are considered important virulence factors for Porphyromonas gingivalis, a bacterium recognized as a major etiologic agent of chronic periodontitis. We investigated the effect of tetracycline and its analogues, doxycycline and minocyclin...

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Main Authors: Imamura, Takahisa, Matsushita, Kenji, Travis, James, Potempa, Jan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90745/
https://ncbi.nlm.nih.gov/pubmed/11557483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2871-2876.2001
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