High Therapeutic Index of Factor C Sushi Peptides: Potent Antimicrobials against Pseudomonas aeruginosa

Factor C protein isolated from the horseshoe crab, Carcinoscorpius rotundicauda, has endotoxin binding capability. Synthetic peptides of 34 amino acids based on the sequence of two regions of factor C (Sushi 1 and Sushi 3) as well as their corresponding mutants exhibited activities against 30 clinic...

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Bibliografiske detaljer
Main Authors: Yau, Yin Hoe, Ho, Bow, Tan, Nguan Soon, Ng, Miang Lon, Ding, Jeak Ling
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90737/
https://ncbi.nlm.nih.gov/pubmed/11557475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2820-2825.2001
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