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A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes

We demonstrate that the transfer of fully charged aminoacyl-tRNAs into peptides directed by the MS2 RNA template requires both ATP and GTP, initiation factors (IF1, IF2, and IF3), elongation factors (EF-Tu, EF-Ts, and EF-G), and the ribosomal ATPase (RbbA). The nonhydrolyzable analogue AMPPCP inhibi...

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Detalles Bibliográficos
Main Authors: Ganoza, M. Clelia, Kiel, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90736/
https://ncbi.nlm.nih.gov/pubmed/11557474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2813-2819.2001
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