A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes

We demonstrate that the transfer of fully charged aminoacyl-tRNAs into peptides directed by the MS2 RNA template requires both ATP and GTP, initiation factors (IF1, IF2, and IF3), elongation factors (EF-Tu, EF-Ts, and EF-G), and the ribosomal ATPase (RbbA). The nonhydrolyzable analogue AMPPCP inhibi...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Ganoza, M. Clelia, Kiel, Michael C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2813-2819.2001
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