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Cellular Uptake of Two Fluoroketolides, HMR 3562 and HMR 3787, by Human Polymorphonuclear Neutrophils In Vitro

We analyzed the cellular accumulation of two new fluoroketolides, HMR 3562 and HMR 3787, by human polymorphonuclear neutrophils (PMN) in vitro. Both compounds were rapidly taken up by PMN, with a cellular-to-extracellular concentration ratio (C/E) of about 141 (HMR 3562) and 117 (HMR 3787) at 5 min,...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Abdelghaffar, H., Vazifeh, D., Labro, M. T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2798-2806.2001
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