Mechanisms and Frequency of Resistance to Gatifloxacin in Comparison to AM-1121 and Ciprofloxacin in Staphylococcus aureus

Gatifloxacin, an 8-methoxyfluoroquinolone, was found to be two- to fourfold more active against wild-type Staphylococcus aureus ISP794 than its desmethoxy derivative, AM-1121, and ciprofloxacin, another desmethoxy fluoroquinolone. Single grlBA mutations caused two- to fourfold increases in the MIC o...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ince, Dilek, Hooper, David C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2755-2764.2001
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