Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses

The orally administered neuraminidase (NA) inhibitor RWJ-270201 was tested in parallel with zanamivir and oseltamivir against a panel of avian influenza viruses for inhibition of NA activity and replication in tissue culture. The agents were then tested for protection of mice against lethal H5N1 and...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Govorkova, Elena A., Leneva, Irina A., Goloubeva, Olga G., Bush, Karen, Webster, Robert G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2723-2732.2001
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