Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses

The orally administered neuraminidase (NA) inhibitor RWJ-270201 was tested in parallel with zanamivir and oseltamivir against a panel of avian influenza viruses for inhibition of NA activity and replication in tissue culture. The agents were then tested for protection of mice against lethal H5N1 and...

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Autori principali: Govorkova, Elena A., Leneva, Irina A., Goloubeva, Olga G., Bush, Karen, Webster, Robert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90723/
https://ncbi.nlm.nih.gov/pubmed/11557461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2723-2732.2001
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