Limonene Arrests Parasite Development and Inhibits Isoprenylation of Proteins in Plasmodium falciparum

Isoprenylation is an essential protein modification in eukaryotic cells. Herein, we report that in Plasmodium falciparum, a number of proteins were labeled upon incubation of intraerythrocytic forms with either [(3)H]farnesyl pyrophosphate or [(3)H]geranylgeranyl pyrophosphate. By thin-layer chromat...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Moura, Ivan Cruz, Wunderlich, Gerhard, Uhrig, Maria L., Couto, Alicia S., Peres, Valnice J., Katzin, Alejandro M., Kimura, Emília A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Action: Physiological Effects
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2553-2558.2001
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