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Mutation in Serratia marcescens AmpC β-Lactamase Producing High-Level Resistance to Ceftazidime and Cefpirome

Starting from a clinical isolate of Serratia marcescens that produced a chromosomally encoded AmpC β-lactamase inducibly, we isolated by stepwise selection two laboratory mutants that showed high levels of resistance to some cephalosporins. The 98R mutant apparently overproduced the unaltered β-lact...

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Bibliografiske detaljer
Main Authors: Raimondi, Alessandro, Sisto, Francesca, Nikaido, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90650/
https://ncbi.nlm.nih.gov/pubmed/11451693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2331-2339.2001
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