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Kinetic Study of Two Novel Enantiomeric Tricyclic β-Lactams Which Efficiently Inactivate Class C β-Lactamases

A detailed kinetic study of the interaction between two ethylidene derivatives of tricyclic carbapenems, Lek 156 and Lek 157, and representative β-lactamases and d-alanyl–d-alanine peptidases (dd-peptidases) is presented. Both compounds are very efficient inactivators of the Enterobacter cloacae 908...

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Autors principals: Vilar, Mateja, Galleni, Moreno, Solmajer, Tom, Turk, Boris, Frère, Jean-Marie, Matagne, André
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90634/
https://ncbi.nlm.nih.gov/pubmed/11451677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2215-2223.2001
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