Domestic Cat Model for Predicting Human Nucleoside Analogue Pharmacokinetics in Blood and Seminal Plasma

To establish whether a feline model can predict nucleoside analogue behavior in human semen, zidovudine (ZDV) and lamivudine (3TC) pharmacokinetic parameters (PKs) were determined in the blood and seminal plasma of healthy cats. Our results show considerable similarity in ZDV and 3TC PKs between cat...

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Detaylı Bibliyografya
Asıl Yazarlar: Jordan, Holly L., Pereira, Arlene S., Cohen, Myron S., Kashuba, Angela D. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC90625/
https://ncbi.nlm.nih.gov/pubmed/11408248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2173-2176.2001
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