Pseudomonas aeruginosa Reveals High Intrinsic Resistance to Penem Antibiotics: Penem Resistance Mechanisms and Their Interplay

Pseudomonas aeruginosa exhibits high intrinsic resistance to penem antibiotics such as faropenem, ritipenem, AMA3176, sulopenem, Sch29482, and Sch34343. To investigate the mechanisms contributing to penem resistance, we used the laboratory strain PAO1 to construct a series of isogenic mutants with a...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Okamoto, Kiyomi, Gotoh, Naomasa, Nishino, Takeshi
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2001
Subjects:	Mechanisms of Resistance
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11408209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.7.1964-1971.2001
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