Activities of Hexadecylphosphocholine (Miltefosine), AmBisome, and Sodium Stibogluconate (Pentostam) against Leishmania donovani in Immunodeficient scid Mice

In both scid and BALB/c mouse-Leishmania donovani models, hexadecyphosphocholine (miltefosine) and AmBisome had similar levels of activity. In contrast, sodium stibogluconate (Pentostam) was significantly less active against L. donovani in scid mice than in BALB/c mice. The in vitro anti-leishmanial...

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Detalhes bibliográficos
Main Authors: Escobar, Patricia, Yardley, Vanessa, Croft, Simon L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90560/
https://ncbi.nlm.nih.gov/pubmed/11353640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1872-1875.2001
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