Activities of Hexadecylphosphocholine (Miltefosine), AmBisome, and Sodium Stibogluconate (Pentostam) against Leishmania donovani in Immunodeficient scid Mice

In both scid and BALB/c mouse-Leishmania donovani models, hexadecyphosphocholine (miltefosine) and AmBisome had similar levels of activity. In contrast, sodium stibogluconate (Pentostam) was significantly less active against L. donovani in scid mice than in BALB/c mice. The in vitro anti-leishmanial...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Escobar, Patricia, Yardley, Vanessa, Croft, Simon L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.6.1872-1875.2001
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