Thalidomide Inhibits Granulocyte Responses in Healthy Humans after Ex Vivo Stimulation with Bacterial Antigens

Ingestion of thalidomide was associated with a reduction in the upregulation of the granulocyte activation marker CD11b and a reduced capacity to release elastase and lactoferrin after stimulation with lipopolysaccharide or lipoteichoic acid. A single oral dose of thalidomide attenuates neutrophil a...

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Autori principali: Juffermans, Nicole P., Verbon, Annelies, Schultz, Marc J., Hack, C. Erik, van Deventer, Sander J. H., Speelman, Peter, van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Biologic Response Modifiers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90503/
https://ncbi.nlm.nih.gov/pubmed/11302825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1547-1549.2001
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