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Enhanced Expression of the Multidrug Efflux Pumps AcrAB and AcrEF Associated with Insertion Element Transposition in Escherichia coli Mutants Selected with a Fluoroquinolone

The development of fluoroquinolone resistance in Escherichia coli may be associated with mutations in regulatory gene loci such as marRAB that lead to increased multidrug efflux, presumably through activation of expression of the AcrAB multidrug efflux pump. We found that multidrug-resistant (MDR) p...

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Autori principali: Jellen-Ritter, A. S., Kern, W. V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90490/
https://ncbi.nlm.nih.gov/pubmed/11302812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1467-1472.2001
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