Enhanced Expression of the Multidrug Efflux Pumps AcrAB and AcrEF Associated with Insertion Element Transposition in Escherichia coli Mutants Selected with a Fluoroquinolone

The development of fluoroquinolone resistance in Escherichia coli may be associated with mutations in regulatory gene loci such as marRAB that lead to increased multidrug efflux, presumably through activation of expression of the AcrAB multidrug efflux pump. We found that multidrug-resistant (MDR) p...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Jellen-Ritter, A. S., Kern, W. V.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11302812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.5.1467-1472.2001
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