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In Vivo Efficacy of Trovafloxacin against Bacteroides fragilis in Mixed Infection with either Escherichia coli or a Vancomycin-Resistant Strain of Enterococcus faecium in an Established-Abscess Murine Model
The pharmacodynamic and pharmacokinetic properties of trovafloxacin were studied in a standardized murine model of established subcutaneous abscesses. Daily dosing regimens of 37.5 to 300 mg/kg every 8 h (q8h) or every 24 h (q24h) were started 3 days after inoculation with mixtures containing either...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
2001
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90479/ https://ncbi.nlm.nih.gov/pubmed/11302801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1394-1401.2001 |
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