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Safety and Pharmacokinetics of Single Doses of (+)-Calanolide A, a Novel, Naturally Occurring Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy, Human Immunodeficiency Virus-Negative Human Subjects

(+)-Calanolide A is a novel, naturally occurring, nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase first isolated from a tropical tree (Calophyllum lanigerum) in the Malaysian rain forest. Previous studies have demonstrated that (+)-calanolide A has specif...

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Main Authors: Creagh, Terri, Ruckle, Jon L., Tolbert, Dwain T., Giltner, Jeremy, Eiznhamer, David A., Dutta, Bipul, Flavin, Michael T., Xu, Ze-Qi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC90477/
https://ncbi.nlm.nih.gov/pubmed/11302799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1379-1386.2001
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