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Circulating Metabolites of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir in Humans: Structural Identification, Levels in Plasma, and Antiviral Activities
Nelfinavir mesylate (Viracept, formally AG1343) is a potent and orally bioavailable human immunodeficiency virus (HIV) type 1 (HIV-1) protease inhibitor (K(i) = 2 nM) and is being widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. The curre...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2001
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90428/ https://ncbi.nlm.nih.gov/pubmed/11257019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1086-1093.2001 |
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