Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

A series of aminodiol inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were identified by using an in vitro peptide cleavage assay. BMS 182,193, BMS 186,318, and BMS 187,071 protected cells against HIV-1, HIV-2, and simian immunodeficiency virus infections, with 50% effective doses...

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Detalhes bibliográficos
Main Authors: Bechtold, C M, Patick, A K, Alam, M, Greytok, J, Tino, J A, Chen, P, Gordon, E, Ahmad, S, Barrish, J C, Zahler, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162546/
https://ncbi.nlm.nih.gov/pubmed/7726501
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