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Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

A series of aminodiol inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were identified by using an in vitro peptide cleavage assay. BMS 182,193, BMS 186,318, and BMS 187,071 protected cells against HIV-1, HIV-2, and simian immunodeficiency virus infections, with 50% effective doses...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Bechtold, C M, Patick, A K, Alam, M, Greytok, J, Tino, J A, Chen, P, Gordon, E, Ahmad, S, Barrish, J C, Zahler, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726501/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.374
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