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Pharmacokinetics and Safety of a 7-Day Administration of Intravenous Itraconazole followed by a 14-Day Administration of Itraconazole Oral Solution in Patients with Hematologic Malignancy

The pharmacokinetics and safety of an intravenous hydroxypropyl-β-cyclodextrin solution of itraconazole administered for 7 days followed by itraconazole oral solution administered at 200 mg once or twice daily for 14 days were assessed in 17 patients with hematologic malignancies. Steady-state plasm...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Boogaerts, Marc A., Maertens, Johan, Van Der Geest, Ronald, Bosly, Andre, Michaux, Jean-Louis, Van Hoof, Achiel, Cleeren, Myriam, Wostenborghs, Robert, De Beule, Karel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90410/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.981-985.2001
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