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Mutations of the Helicobacter pylori Genes rdxA and pbp1 Cause Resistance against Metronidazole and Amoxicillin

To investigate amoxicillin and metronidazole resistance of Helicobacter pylori, we compared putative resistance genes between resistant strains obtained in vitro and their sensitive parent strain. All metronidazole-resistant strains had rdxA mutations, and an amoxicillin-resistant strain had pbp1 an...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Paul, Ralf, Postius, Stefan, Melchers, Klaus, Schäfer, Klaus P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90405/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.962-965.2001
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