Mutations of the Helicobacter pylori Genes rdxA and pbp1 Cause Resistance against Metronidazole and Amoxicillin

To investigate amoxicillin and metronidazole resistance of Helicobacter pylori, we compared putative resistance genes between resistant strains obtained in vitro and their sensitive parent strain. All metronidazole-resistant strains had rdxA mutations, and an amoxicillin-resistant strain had pbp1 an...

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Autori principali: Paul, Ralf, Postius, Stefan, Melchers, Klaus, Schäfer, Klaus P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90405/
https://ncbi.nlm.nih.gov/pubmed/11181392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.962-965.2001
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