New Mutation in ParE in a Pneumococcal In Vitro Mutant Resistant to Fluoroquinolones

For an in vitro mutant of Streptococcus pneumoniae selected on moxifloxacin four- to eightfold-increased MICs of new fluoroquinolones, only a twofold-increased MIC of ciprofloxacin, and a twofold-decreased MIC of novobiocin were observed. This phenotype was conferred by two mutations: Ser81Phe in Gy...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Janoir, Claire, Varon, Emmanuelle, Kitzis, Marie-Dominique, Gutmann, Laurent
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Mechanisms of Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90402/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.952-955.2001
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