In Vivo Influenza Virus-Inhibitory Effects of the Cyclopentane Neuraminidase Inhibitor RWJ-270201

The cyclopentane influenza virus neuraminidase inhibitor RWJ-270201 was evaluated against influenza A/NWS/33 (H1N1), A/Shangdong/09/93 (H3N2), A/Victoria/3/75 (H3N2), and B/Hong Kong/05/72 virus infections in mice. Treatment was by oral gavage twice daily for 5 days beginning 4 h pre-virus exposure....

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Autors principals: Sidwell, Robert W., Smee, Donald F., Huffman, John H., Barnard, Dale L., Bailey, Kevin W., Morrey, John D., Babu, Y. S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90368/
https://ncbi.nlm.nih.gov/pubmed/11181355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.749-757.2001
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