Cyclopentane Neuraminidase Inhibitors with Potent In Vitro Anti-Influenza Virus Activities

A novel series of cyclopentane derivatives have been found to exhibit potent and selective inhibitory effects on influenza virus neuraminidase. These compounds, designated RWJ-270201, BCX-1827, BCX-1898, and BCX-1923, were tested in parallel with zanamivir and oseltamivir carboxylate against a spect...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Smee, Donald F., Huffman, John H., Morrison, Ann C., Barnard, Dale L., Sidwell, Robert W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.743-748.2001
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