Compartmental Pharmacokinetics of the Antifungal Echinocandin Caspofungin (MK-0991) in Rabbits

The pharmacokinetics of the antifungal echinocandin-lipopeptide caspofungin (MK-0991) in plasma were studied in groups of three healthy rabbits after single and multiple daily intravenous administration of doses of 1, 3, and 6 mg/kg of body weight. Concentrations were measured by a validated high-pe...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Groll, Andreas H., Gullick, Bryan M., Petraitiene, Ruta, Petraitis, Vidmantas, Candelario, Myrna, Piscitelli, Stephen C., Walsh, Thomas J.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90333/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.596-600.2001
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