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Pharmacokinetic Interaction between Amprenavir and Rifabutin or Rifampin in Healthy Males

The objective of this study was to determine if there is a pharmacokinetic interaction when amprenavir is given with rifabutin or rifampin and to determine the effects of these drugs on the erythromycin breath test (ERMBT). Twenty-four healthy male subjects were randomized to one of two cohorts. All...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Polk, Ronald E., Brophy, Donald F., Israel, Debra S., Patron, Roberto, Sadler, Brian M., Chittick, Gregory E., Symonds, William T., Lou, Yu, Kristoff, Debbie, Stein, D. S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.502-508.2001
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