Dosage-Dependent Antifungal Efficacy of V-Echinocandin (LY303366) against Experimental Fluconazole-Resistant Oropharyngeal and Esophageal Candidiasis

V-echinocandin (VER-002; LY303366) is a semisynthetic derivative of echinocandin B and a potent inhibitor of fungal (1, 3)-β-d-glucan synthase. We studied the antifungal efficacy, the concentrations in saliva and tissue, and the safety of VER-002 at escalating dosages against experimental oropharyng...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Petraitis, Vidmantas, Petraitiene, Ruta, Groll, Andreas H., Sein, Tin, Schaufele, Robert L., Lyman, Caron A., Francesconi, Andrea, Bacher, John, Piscitelli, Stephen C., Walsh, Thomas J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Experimental Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.471-479.2001
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