Cross-Resistance between Triclosan and Antibiotics in Pseudomonas aeruginosa Is Mediated by Multidrug Efflux Pumps: Exposure of a Susceptible Mutant Strain to Triclosan Selects nfxB Mutants Overexpressing MexCD-OprJ

Triclosan is an antiseptic frequently added to items as diverse as soaps, lotions, toothpaste, and many commonly used household fabrics and plastics. Although wild-type Pseudomonas aeruginosa expresses the triclosan target enoyl-acyl carrier protein reductase, it is triclosan resistant due to expres...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Chuanchuen, Rungtip, Beinlich, Kerry, Hoang, Tung T., Becher, Anna, Karkhoff-Schweizer, RoxAnn R., Schweizer, Herbert P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.428-432.2001
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