Effective Combination Therapy for Invasive Pneumococcal Pneumonia with Ampicillin and Intravenous Immunoglobulins in a Mouse Model

Intranasal immunotherapy for Streptococcus pneumoniae invasive pneumonia with polyvalent immunoglobulins (IVIG) was effective in mice against pneumonia but failed to prevent bacteremia. The combination of subcurative doses of IVIG and of ampicillin was fully protective. Such an approach, successfull...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	De Hennezel, Laetitia, Ramisse, Françoise, Binder, Patrice, Marchal, Gilles, Alonso, Jean-Michel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.316-318.2001
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